Triple agonist targeting GLP-1, GIP, and glucagon receptors. Next-generation metabolic peptide with potentially the most potent weight loss effects. Also targets liver fat directly via glucagon. MUST be titrated slowly — start at 0.5mg weekly and work up based on tolerance. Doses above 4mg are rarely necessary for most users and significantly increase side effect risk.
Inject SubQ once weekly, same day each week. STRICT titration: 0.5mg x4wk → 1mg x4wk → 2mg x4wk → 3mg x4wk → 4mg maintenance. Only advance dose if GI side effects are tolerable. Most users respond well at 2-4mg/week — 6mg+ is only for clinical trial contexts and carries significantly higher nausea, vomiting, and liver stress risk. Monitor liver enzymes (ALT/AST) every 4-6 weeks.
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