Acetyl Hexapeptide (Argireline)

Dosage

50-100ppm (topical)

Frequency

Daily (topical)

Cycle

Ongoing

What is Acetyl Hexapeptide (Argireline)?

Synthetic hexapeptide (Acetyl Hexapeptide-3) that competitively inhibits SNARE complex assembly (SNAP-25/synaptobrevin/syntaxin trimer) at the neuromuscular junction. Blocks acetylcholine vesicle fusion and release in facial expression muscles (frontalis, orbicularis oculi, corrugator supercilii), creating a localized mild botox-like effect that reduces muscle contraction amplitude. Smooths expression lines on forehead, crow's feet, and between eyebrows. Reversible, non-toxic, no systemic absorption.

How to Use Acetyl Hexapeptide (Argireline)

Apply topically to face, focusing on expression line areas (forehead, crow's feet). Twice daily. Not injectable. Consistent use needed — effects reverse on discontinuation.